The systematic study of circulating tumor cell isolation using lithographic microfilters
نویسندگان
چکیده
منابع مشابه
Circulating Tumor Cell Isolation and Analysis.
Isolation and analysis of cancer cells from body fluids have significant implications in diagnosis and therapeutic treatment of cancers. Circulating tumor cells (CTCs) are cancer cells circulating in the peripheral blood or spreading iatrogenically into blood vessels, which is an early step in the cascade of events leading to cancer metastasis. Therefore, CTCs can be used for diagnosing for the...
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Circulating tumor cells (CTCs) separation technology has made positive impacts on cancer science in many aspects. The ability of detecting and separating CTCs can play a key role in early cancer detection and treatment. In recent years, there has been growing interest in using deformability-based CTC separation microfilters due to their simplicity and low cost. Most of the previous studies in t...
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Integrating nanotechnology with established cancer research provides extraordinary opportunities to find essential breakthroughs in the fight against cancer. Nanowires and nanotubes are among the leading approaches under development for biological applications. Till now, the nanodevices face a key challenge to develop surfaces and structures that can be chemically modified for specific conjugat...
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Presence and frequency of rare circulating tumor cells (CTCs) in bloodstreams of cancer patients are pivotal to early cancer detection and treatment monitoring. Here, we use a spiral microchannel with inherent centrifugal forces for continuous, size-based separation of CTCs from blood (Dean Flow Fractionation (DFF)) which facilitates easy coupling with conventional downstream biological assays....
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It took almost 150 years after the first report on the presence of circulating tumor cells (CTCs) by Thomas Ashworth in 1869 (1 ) to reach the point at which their detection and molecular characterization is one of the hottest fields in cancer research (2 ). The clinical significance of CTCs has been evaluated in many types of solid cancers, and the Food and Drug Administration (FDA) cleared th...
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ژورنال
عنوان ژورنال: RSC Adv.
سال: 2014
ISSN: 2046-2069
DOI: 10.1039/c3ra46839a